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The impact of estimated tumour purity on gene expression-based drug repositioning of Clear Cell Renal Cell Carcinoma samples

To find new potentially therapeutic drugs against clear cell Renal Cell Carcinoma (ccRCC), within drugs currently prescribed for other diseases (drug repositioning), we previously searched for drugs which are expected to bring the gene expression of 500 + ccRCC samples from The Cancer Genome Atlas c...

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Detalles Bibliográficos
Autores principales: Koudijs, Karel K. M., Terwisscha van Scheltinga, Anton G. T., Böhringer, Stefan, Schimmel, Kirsten J. M., Guchelaar, Henk-Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385172/
https://www.ncbi.nlm.nih.gov/pubmed/30792476
http://dx.doi.org/10.1038/s41598-019-39891-y