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Downregulation of Npas4 in parvalbumin interneurons and cognitive deficits after neonatal NMDA receptor blockade: relevance for schizophrenia

Dysfunction of prefrontal parvalbumin (PV+) interneurons has been linked with severe cognitive deficits as observed in several neurodevelopmental disorders including schizophrenia. However, whether a specific aspect of PV+ neurons deregulation, or a specific molecular mechanism within PV+ neurons is...

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Detalles Bibliográficos
Autores principales:	Shepard, Ryan, Heslin, Kelsey, Hagerdorn, Payton, Coutellier, Laurence
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385315/ https://www.ncbi.nlm.nih.gov/pubmed/30792384 http://dx.doi.org/10.1038/s41398-019-0436-3

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