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STAT1 signaling shields T cells from NK cell-mediated cytotoxicity
The JAK-STAT pathway critically regulates T-cell differentiation, and STAT1 is postulated to regulate several immune-mediated diseases by inducing proinflammatory subsets. Here we show that STAT1 enables CD4(+) T-cell-mediated intestinal inflammation by protecting them from natural killer (NK) cell-...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385318/ https://www.ncbi.nlm.nih.gov/pubmed/30796216 http://dx.doi.org/10.1038/s41467-019-08743-8 |