Cargando…

Reduced hepatocellular lipid accumulation and energy metabolism in patients with long standing type 1 diabetes mellitus

The prevalence of obesity and metabolic syndrome increases in patients with type 1 diabetes mellitus (T1DM). In the general population this is linked with ectopic lipid accumulation in liver (HCL) and skeletal muscle (IMCL), representing hallmarks in the development of insulin resistance. Moreover,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wolf, Peter, Fellinger, Paul, Pfleger, Lorenz, Smajis, Sabina, Beiglböck, Hannes, Gajdošík, Martin, Anderwald, Christian-Heinz, Trattnig, Siegfried, Luger, Anton, Winhofer, Yvonne, Krššák, Martin, Krebs, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385341/ https://www.ncbi.nlm.nih.gov/pubmed/30796305 http://dx.doi.org/10.1038/s41598-019-39362-4

Ejemplares similares

Pericardial- Rather than Intramyocardial Fat Is Independently Associated with Left Ventricular Systolic Heart Function in Metabolically Healthy Humans
por: Wolf, Peter, et al.
Publicado: (2016)

Absolute Quantification of Phosphor‐Containing Metabolites in the Liver Using (31)P MRSI and Hepatic Lipid Volume Correction at 7T Suggests No Dependence on Body Mass Index or Age
por: Pfleger, Lorenz, et al.
Publicado: (2018)

Plasma renin levels are associated with cardiac function in primary adrenal insufficiency
por: Wolf, Peter, et al.
Publicado: (2019)

Increased GH/IGF-I Axis Activity Relates to Lower Hepatic Lipids and Phosphor Metabolism
por: Fellinger, Paul, et al.
Publicado: (2023)

Short-Term Hyperinsulinemia and Hyperglycemia Increase Myocardial Lipid Content in Normal Subjects
por: Winhofer, Yvonne, et al.
Publicado: (2012)

Effects of Insulin Therapy on Myocardial Lipid Content and Cardiac Geometry in Patients with Type-2 Diabetes Mellitus
por: Jankovic, Drazenka, et al.
Publicado: (2012)

Hepatic Rather Than Cardiac Steatosis Relates to Glucose Intolerance in Women with Prior Gestational Diabetes
por: Winhofer, Yvonne, et al.
Publicado: (2014)

Feasibility of Hepatic Fat Quantification Using Proton Density Fat Fraction by Multi-Echo Chemical-Shift-Encoded MRI at 7T
por: Kořínek, Radim, et al.
Publicado: (2021)

In Vivo (1)H MR Spectroscopy of Biliary Components of Human Gallbladder at 7T
por: Gajdošík, Martin, et al.
Publicado: (2020)

OR06-05 Inadequate High Mitochondrial ATP-Synthesis Explains “Non-Fatty-Liver” in Patients with Acromegaly
por: Fellinger, Paul, et al.
Publicado: (2020)

Repeatability assessment of sodium ((23)Na) MRI at 7.0 T in healthy human calf muscle and preliminary results on tissue sodium concentrations in subjects with Addison’s disease
por: Zaric, Olgica, et al.
Publicado: (2022)

Whole-Body Insulin Sensitivity Rather than Body-Mass-Index Determines Fasting and Post-Glucose-Load Growth Hormone Concentrations
por: Anderwald, Christian-Heinz, et al.
Publicado: (2014)

Overweight and obesity in type 1 diabetes equal those of the general population
por: Fellinger, Paul, et al.
Publicado: (2019)

Heart, lipids and hormones
por: Wolf, Peter, et al.
Publicado: (2017)

Glucose Absorption in Gestational Diabetes Mellitus During an Oral Glucose Tolerance Test
por: Anderwald, Christian, et al.
Publicado: (2011)

Detection and Alterations of Acetylcarnitine in Human Skeletal Muscles by 1H MRS at 7 T
por: Klepochová, Radka, et al.
Publicado: (2017)

Micro- and macrovascular function in patients suffering from primary adrenal insufficiency: a cross-sectional case–control study
por: Müller, M., et al.
Publicado: (2020)

Ultralong TE In Vivo (1)H MR Spectroscopy of Omega‐3 Fatty Acids in Subcutaneous Adipose Tissue at 7 T
por: Gajdošík, Martin, et al.
Publicado: (2018)

Adequately Adapted Insulin Secretion and Decreased Hepatic Insulin Extraction Cause Elevated Insulin Concentrations in Insulin Resistant Non-Diabetic Adrenal Incidentaloma Patients
por: Anderwald, Christian-Heinz, et al.
Publicado: (2013)

Pre-operative Obesity-Associated Hyperandrogenemia in Women and Hypogonadism in Men Have No Impact on Weight Loss Following Bariatric Surgery
por: Beiglböck, Hannes, et al.
Publicado: (2020)

Switch to Combined GLP1 Receptor Agonist Lixisenatide with Basal Insulin Glargine in Poorly Controlled T2DM Patients with Premixed Insulin Therapy: A Clinical Observation and Pilot Study in Nine Patients
por: Harreiter, Jürgen, et al.
Publicado: (2017)

Muscle‐Specific Relation of Acetylcarnitine and Intramyocellular Lipids to Chronic Hyperglycemia: A Pilot 3‐T (1)H MRS Study
por: Klepochová, Radka, et al.
Publicado: (2020)

Chronic Peripheral Hyperinsulinemia in Type 1 Diabetic Patients After Successful Combined Pancreas-Kidney Transplantation Does Not Affect Ectopic Lipid Accumulation in Skeletal Muscle and Liver
por: Stadler, Marietta, et al.
Publicado: (2010)

Differences in Muscle Metabolism Between Triathletes and Normally Active Volunteers Investigated Using Multinuclear Magnetic Resonance Spectroscopy at 7T
por: Klepochová, Radka, et al.
Publicado: (2018)

Psychopharmacological Medication Has No Influence on Vitamin Status After Bariatric Surgery in Long-term Follow-up
por: Beiglböck, Hannes, et al.
Publicado: (2020)

Ultra‐high‐field magnetic resonance spectroscopy in non‐alcoholic fatty liver disease: Novel mechanistic and diagnostic insights of energy metabolism in non‐alcoholic steatohepatitis and advanced fibrosis
por: Traussnigg, Stefan, et al.
Publicado: (2017)

Insulin Infusion During Normoglycemia Modulates Insulin Secretion According to Whole-Body Insulin Sensitivity
por: Anderwald, Christian, et al.
Publicado: (2011)

Feasibility and repeatability of localized (31)P‐MRS four‐angle saturation transfer (FAST) of the human gastrocnemius muscle using a surface coil at 7 T
por: Tušek Jelenc, Marjeta, et al.
Publicado: (2016)

Alterations in Gastrointestinal, Endocrine, and Metabolic Processes After Bariatric Roux-en-Y Gastric Bypass Surgery
por: Anderwald, Christian-Heinz, et al.
Publicado: (2012)

Lipid suppression via double inversion recovery with symmetric frequency sweep for robust 2D‐GRAPPA‐accelerated MRSI of the brain at 7 T
por: Hangel, Gilbert, et al.
Publicado: (2015)

Skeletal muscle alkaline Pi pool is decreased in overweight-to-obese sedentary subjects and relates to mitochondrial capacity and phosphodiester content
por: Valkovič, Ladislav, et al.
Publicado: (2016)

HbA1c and Glucose Management Indicator Discordance Associated with Obesity and Type 2 Diabetes in Intermittent Scanning Glucose Monitoring System
por: Fellinger, Paul, et al.
Publicado: (2022)

Ectopic lipid metabolism in anterior pituitary dysfunction
por: Baumgartner, Clemens, et al.
Publicado: (2023)

Proton-decoupled carbon magnetic resonance spectroscopy in human calf muscles at 7 T using a multi-channel radiofrequency coil
por: Goluch, Sigrun, et al.
Publicado: (2018)

Sex-Specific Differences in Mortality of Patients with a History of Bariatric Surgery: a Nation-Wide Population-Based Study
por: Beiglböck, Hannes, et al.
Publicado: (2021)

Dynamic (31)P–MRSI using spiral spectroscopic imaging can map mitochondrial capacity in muscles of the human calf during plantar flexion exercise at 7 T
por: Valkovič, Ladislav, et al.
Publicado: (2016)

Ectopic Cushing’s syndrome in a patient with inferior petrosal sinus sampling indicating pituitary‐dependent ACTH secretion
por: Micko, Alexander, et al.
Publicado: (2019)

Osteocalcin Is Related to Enhanced Insulin Secretion in Gestational Diabetes Mellitus
por: Winhofer, Yvonne, et al.
Publicado: (2010)

Improved spectral resolution and high reliability of in vivo (1)H MRS at 7 T allow the characterization of the effect of acute exercise on carnosine in skeletal muscle
por: Just Kukurová, Ivica, et al.
Publicado: (2015)

Simultaneous Multiple Resonance Frequency imaging (SMURF): Fat‐water imaging using multi‐band principles
por: Bachrata, Beata, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_sn48aaq5agch2b57ddfbks1d9b