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Glycerol kinase 5 confers gefitinib resistance through SREBP1/SCD1 signaling pathway

BACKGROUND: Drug resistance is common in cancer chemotherapy. This study investigates the role of Glycerol kinase 5 (GK5) in mediating gefitinib resistance in NSCLC. METHODS: The exosomal mRNA of GK5 was detected using a tethered cationic lipoplex nanoparticle (TCLN) biochip. Real-time PCR and Weste...

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Detalles Bibliográficos
Autores principales:	Zhou, Jian, Qu, Guimei, Zhang, Ge, Wu, Zuoren, Liu, Jing, Yang, Dawei, Li, Jing, Chang, Meijia, Zeng, Hengshan, Hu, Jie, Fang, Tao, Song, Yuanlin, Bai, Chunxue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385389/ https://www.ncbi.nlm.nih.gov/pubmed/30791926 http://dx.doi.org/10.1186/s13046-019-1057-7

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