Dose-painting multicenter phase III trial in newly diagnosed glioblastoma: the SPECTRO-GLIO trial comparing arm A standard radiochemotherapy to arm B radiochemotherapy with simultaneous integrated boost guided by MR spectroscopic imaging

BACKGROUND: Glioblastoma, a high-grade glial infiltrating tumor, is the most frequent malignant brain tumor in adults and carries a dismal prognosis. External beam radiotherapy (EBRT) increases overall survival but this is still low due to local relapses, mostly occurring in the irradiation field. A...

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Detalles Bibliográficos
Autores principales: Laprie, Anne, Ken, Soléakhéna, Filleron, Thomas, Lubrano, Vincent, Vieillevigne, Laure, Tensaouti, Fatima, Catalaa, Isabelle, Boetto, Sergio, Khalifa, Jonathan, Attal, Justine, Peyraga, Guillaume, Gomez-Roca, Carlos, Uro-Coste, Emmanuelle, Noel, Georges, Truc, Gilles, Sunyach, Marie-Pierre, Magné, Nicolas, Charissoux, Marie, Supiot, Stéphane, Bernier, Valérie, Mounier, Muriel, Poublanc, Muriel, Fabre, Amandine, Delord, Jean-Pierre, Cohen-Jonathan Moyal, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385401/
https://www.ncbi.nlm.nih.gov/pubmed/30791889
http://dx.doi.org/10.1186/s12885-019-5317-x

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