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A mathematical model of iron import and trafficking in wild-type and Mrs3/4ΔΔ yeast cells

BACKGROUND: Iron plays crucial roles in the metabolism of eukaryotic cells. Much iron is trafficked into mitochondria where it is used for iron-sulfur cluster assembly and heme biosynthesis. A yeast strain in which Mrs3/4, the high-affinity iron importers on the mitochondrial inner membrane, are del...

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Detalles Bibliográficos
Autores principales: Wofford, Joshua D., Lindahl, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385441/
https://www.ncbi.nlm.nih.gov/pubmed/30791941
http://dx.doi.org/10.1186/s12918-019-0702-2