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A mathematical model of iron import and trafficking in wild-type and Mrs3/4ΔΔ yeast cells
BACKGROUND: Iron plays crucial roles in the metabolism of eukaryotic cells. Much iron is trafficked into mitochondria where it is used for iron-sulfur cluster assembly and heme biosynthesis. A yeast strain in which Mrs3/4, the high-affinity iron importers on the mitochondrial inner membrane, are del...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385441/ https://www.ncbi.nlm.nih.gov/pubmed/30791941 http://dx.doi.org/10.1186/s12918-019-0702-2 |