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MicroRNA-506 inhibits tumor growth and metastasis in nasopharyngeal carcinoma through the inactivation of the Wnt/β-catenin signaling pathway by down-regulating LHX2

BACKGROUND: Epithelial-mesenchymal transition (EMT)-associated proteins play key roles in cancer progression and metastasis with the involvement of microRNAs (miRNAs). This study aims to assess the role of miR-506 working in tandem with LIM Homeobox 2 (LHX2) in EMT and metastasis through the Wnt/β-c...

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Detalles Bibliográficos
Autores principales: Liang, Tian-Song, Zheng, Ying-Juan, Wang, Juan, Zhao, Jing-Yi, Yang, Dao-Ke, Liu, Zhang-Suo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385449/
https://www.ncbi.nlm.nih.gov/pubmed/30791932
http://dx.doi.org/10.1186/s13046-019-1023-4