Reproducible inference of transcription factor footprints in ATAC-seq and DNase-seq datasets using protocol-specific bias modeling

BACKGROUND: DNase-seq and ATAC-seq are broadly used methods to assay open chromatin regions genome-wide. The single nucleotide resolution of DNase-seq has been further exploited to infer transcription factor binding sites (TFBSs) in regulatory regions through footprinting. Recent studies have demons...

Descripción completa

Detalles Bibliográficos
Autores principales: Karabacak Calviello, Aslıhan, Hirsekorn, Antje, Wurmus, Ricardo, Yusuf, Dilmurat, Ohler, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385462/
https://www.ncbi.nlm.nih.gov/pubmed/30791920
http://dx.doi.org/10.1186/s13059-019-1654-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385462/
https://www.ncbi.nlm.nih.gov/pubmed/30791920
http://dx.doi.org/10.1186/s13059-019-1654-y

Ejemplares similares