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Rhodamine–Hoechst positional isomers for highly efficient staining of heterochromatin
Hoechst conjugates to fluorescent dyes are popular DNA stains for live-cell imaging, but the relationship between their structure and performance remains elusive. This study of carboxyrhodamine–Hoechst 33258 conjugates reveals that a minimal change in the attachment point of the dye has dramatic eff...
Autores principales: | Bucevičius, Jonas, Keller-Findeisen, Jan, Gilat, Tanja, Hell, Stefan W., Lukinavičius, Gražvydas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385482/ https://www.ncbi.nlm.nih.gov/pubmed/30881625 http://dx.doi.org/10.1039/c8sc05082a |
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