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Transcriptomic profiles of retinal ganglion cells are defined by the magnitude of intraocular pressure elevation in adult mice
Elevated intraocular pressure (IOP) is the major risk factor for glaucoma, a sight threatening disease of retinal ganglion cells (RGCs) and their axons. Despite the central importance of IOP, details of the impact of IOP elevation on RGC gene expression remain elusive. We developed a 4-step immunopa...
Autores principales: | Park, Yong H., Snook, Joshua D., Ostrin, Edwin J., Kim, Sangbae, Chen, Rui, Frankfort, Benjamin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385489/ https://www.ncbi.nlm.nih.gov/pubmed/30796289 http://dx.doi.org/10.1038/s41598-019-39141-1 |
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