Merkel Cells: A Collective Review of Current Concepts

Merkel cells (MCs) constitute a very unique population of postmitotic cells scattered along the dermo-epidermal junction. These cells that have synaptic contacts with somatosensory afferents are regarded to have a pivotal role in sensory discernment. Several concerns exist till date as to their orig...

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Detalles Bibliográficos
Autores principales: Abraham, Jacob, Mathew, Sherin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Education Forum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385537/
https://www.ncbi.nlm.nih.gov/pubmed/30820413
http://dx.doi.org/10.4103/ijabmr.IJABMR_34_18
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author Abraham, Jacob
Mathew, Sherin
author_facet Abraham, Jacob
Mathew, Sherin
author_sort Abraham, Jacob
collection PubMed
description Merkel cells (MCs) constitute a very unique population of postmitotic cells scattered along the dermo-epidermal junction. These cells that have synaptic contacts with somatosensory afferents are regarded to have a pivotal role in sensory discernment. Several concerns exist till date as to their origin, multiplication, and relevance in skin biology. The article, a collective review of literature extracted from PubMed search and dermatology books, provides novel insights into the physiology of MCs and their recent advances.
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spelling pubmed-63855372019-02-28 Merkel Cells: A Collective Review of Current Concepts Abraham, Jacob Mathew, Sherin Int J Appl Basic Med Res Education Forum Merkel cells (MCs) constitute a very unique population of postmitotic cells scattered along the dermo-epidermal junction. These cells that have synaptic contacts with somatosensory afferents are regarded to have a pivotal role in sensory discernment. Several concerns exist till date as to their origin, multiplication, and relevance in skin biology. The article, a collective review of literature extracted from PubMed search and dermatology books, provides novel insights into the physiology of MCs and their recent advances. Medknow Publications & Media Pvt Ltd 2019 /pmc/articles/PMC6385537/ /pubmed/30820413 http://dx.doi.org/10.4103/ijabmr.IJABMR_34_18 Text en Copyright: © 2019 International Journal of Applied and Basic Medical Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Education Forum
Abraham, Jacob
Mathew, Sherin
Merkel Cells: A Collective Review of Current Concepts
title Merkel Cells: A Collective Review of Current Concepts
title_full Merkel Cells: A Collective Review of Current Concepts
title_fullStr Merkel Cells: A Collective Review of Current Concepts
title_full_unstemmed Merkel Cells: A Collective Review of Current Concepts
title_short Merkel Cells: A Collective Review of Current Concepts
title_sort merkel cells: a collective review of current concepts
topic Education Forum
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385537/
https://www.ncbi.nlm.nih.gov/pubmed/30820413
http://dx.doi.org/10.4103/ijabmr.IJABMR_34_18
work_keys_str_mv AT abrahamjacob merkelcellsacollectivereviewofcurrentconcepts
AT mathewsherin merkelcellsacollectivereviewofcurrentconcepts

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