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Lysine carbonylation is a previously unrecognized contributor to peroxidase activation of cytochrome c by chloramine-T
The peroxidase activity of cytochrome c (cyt c) plays a key role during apoptosis. Peroxidase catalysis requires a vacant Fe coordination site, i.e., cyt c must undergo an activation process involving structural changes that rupture the native Met80–Fe contact. A common strategy for dissociating thi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385661/ https://www.ncbi.nlm.nih.gov/pubmed/30881663 http://dx.doi.org/10.1039/c8sc03624a |