Peripheral Mechanisms Mediating the Sustained Antidiabetic Action of FGF1 in the Brain

We recently reported that in rodent models of type 2 diabetes (T2D), a single intracerebroventricular (icv) injection of fibroblast growth factor 1 (FGF1) induces remission of hyperglycemia that is sustained for weeks. To clarify the peripheral mechanisms underlying this effect, we used the Zucker d...

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Detalles Bibliográficos
Autores principales: Scarlett, Jarrad M., Muta, Kenjiro, Brown, Jenny M., Rojas, Jennifer M., Matsen, Miles E., Acharya, Nikhil K., Secher, Anna, Ingvorsen, Camilla, Jorgensen, Rasmus, Høeg-Jensen, Thomas, Stefanovski, Darko, Bergman, Richard N., Piccinini, Francesca, Kaiyala, Karl J., Shiota, Masakazu, Morton, Gregory J., Schwartz, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2019
Materias:
Pharmacology and Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385755/
https://www.ncbi.nlm.nih.gov/pubmed/30523024
http://dx.doi.org/10.2337/db18-0498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385755/
https://www.ncbi.nlm.nih.gov/pubmed/30523024
http://dx.doi.org/10.2337/db18-0498

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