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Análise do Sistema de Informação da Vigilância de Eventos Adversos Pós-Vacinação no Brasil, 2014 a 2016

OBJECTIVE: To describe the characteristics of vaccine adverse events (VAE) reports in the online VAE Reporting System (VAE-RS) after 2 years of operation. METHOD: A descriptive analysis of VAE reports entered into the VAE-RS between July 2014 and June 2016 was performed. RESULTS: During the study pe...

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Autores principales: Pacheco, Flávia Caselli, Domingues, Carla Magda Allan Santos, Maranhão, Ana Goretti Kalume, Carvalho, Sandra Maria Deotti, Teixeira, Antonia Maria da Silva, Braz, Rui Moreira, Rebelo, Renata Cristina Freitas, Guilhem, Dirce Bellezi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Organización Panamericana de la Salud 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385780/
https://www.ncbi.nlm.nih.gov/pubmed/31093041
http://dx.doi.org/10.26633/RPSP.2018.12
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author Pacheco, Flávia Caselli
Domingues, Carla Magda Allan Santos
Maranhão, Ana Goretti Kalume
Carvalho, Sandra Maria Deotti
Teixeira, Antonia Maria da Silva
Braz, Rui Moreira
Rebelo, Renata Cristina Freitas
Guilhem, Dirce Bellezi
author_facet Pacheco, Flávia Caselli
Domingues, Carla Magda Allan Santos
Maranhão, Ana Goretti Kalume
Carvalho, Sandra Maria Deotti
Teixeira, Antonia Maria da Silva
Braz, Rui Moreira
Rebelo, Renata Cristina Freitas
Guilhem, Dirce Bellezi
author_sort Pacheco, Flávia Caselli
collection PubMed
description OBJECTIVE: To describe the characteristics of vaccine adverse events (VAE) reports in the online VAE Reporting System (VAE-RS) after 2 years of operation. METHOD: A descriptive analysis of VAE reports entered into the VAE-RS between July 2014 and June 2016 was performed. RESULTS: During the study period, 24 732 VAE were reported. Of 5 570 Brazilian municipalities, 2 571 (46.2%) reported at least one VAE; however, only 1 622 (6.6%) reports had been completed/closed at the end of the study period. Of these, 89.9% referred to mild VAE. Among the completed reports, 19.7% did not provide information on “type of medical care provided,” and 98.7% had no information regarding laboratory tests. Systemic neurological symptoms were the most frequent serious VAE among closed reports (59.5% of serious signs/symptoms). Concerning age, the highest VAE reporting coefficients were recorded for children aged ≤ 4 years. CONCLUSION: The VAE-RS is useful to monitor immunization safety. However, municipal services must increase adherence to the system and perform the required investigation and reporting of VAE, with timely and adequate completion of the VAE-RS form. Knowledge regarding VAE can be used in the daily routine of surveillance services, improving the safety of immunobiological agents.
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spelling pubmed-63857802019-05-15 Análise do Sistema de Informação da Vigilância de Eventos Adversos Pós-Vacinação no Brasil, 2014 a 2016 Pacheco, Flávia Caselli Domingues, Carla Magda Allan Santos Maranhão, Ana Goretti Kalume Carvalho, Sandra Maria Deotti Teixeira, Antonia Maria da Silva Braz, Rui Moreira Rebelo, Renata Cristina Freitas Guilhem, Dirce Bellezi Rev Panam Salud Publica Artigo Original OBJECTIVE: To describe the characteristics of vaccine adverse events (VAE) reports in the online VAE Reporting System (VAE-RS) after 2 years of operation. METHOD: A descriptive analysis of VAE reports entered into the VAE-RS between July 2014 and June 2016 was performed. RESULTS: During the study period, 24 732 VAE were reported. Of 5 570 Brazilian municipalities, 2 571 (46.2%) reported at least one VAE; however, only 1 622 (6.6%) reports had been completed/closed at the end of the study period. Of these, 89.9% referred to mild VAE. Among the completed reports, 19.7% did not provide information on “type of medical care provided,” and 98.7% had no information regarding laboratory tests. Systemic neurological symptoms were the most frequent serious VAE among closed reports (59.5% of serious signs/symptoms). Concerning age, the highest VAE reporting coefficients were recorded for children aged ≤ 4 years. CONCLUSION: The VAE-RS is useful to monitor immunization safety. However, municipal services must increase adherence to the system and perform the required investigation and reporting of VAE, with timely and adequate completion of the VAE-RS form. Knowledge regarding VAE can be used in the daily routine of surveillance services, improving the safety of immunobiological agents. Organización Panamericana de la Salud 2018-02-28 /pmc/articles/PMC6385780/ /pubmed/31093041 http://dx.doi.org/10.26633/RPSP.2018.12 Text en https://creativecommons.org/licenses/by-nc-nd/3.0/igo/legalcode This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 IGO License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited. No modifications or commercial use of this article are permitted. In any reproduction of this article there should not be any suggestion that PAHO or this article endorse any specific organization or products. The use of the PAHO logo is not permitted. This notice should be preserved along with the article's original URL.
spellingShingle Artigo Original
Pacheco, Flávia Caselli
Domingues, Carla Magda Allan Santos
Maranhão, Ana Goretti Kalume
Carvalho, Sandra Maria Deotti
Teixeira, Antonia Maria da Silva
Braz, Rui Moreira
Rebelo, Renata Cristina Freitas
Guilhem, Dirce Bellezi
Análise do Sistema de Informação da Vigilância de Eventos Adversos Pós-Vacinação no Brasil, 2014 a 2016
title Análise do Sistema de Informação da Vigilância de Eventos Adversos Pós-Vacinação no Brasil, 2014 a 2016
title_full Análise do Sistema de Informação da Vigilância de Eventos Adversos Pós-Vacinação no Brasil, 2014 a 2016
title_fullStr Análise do Sistema de Informação da Vigilância de Eventos Adversos Pós-Vacinação no Brasil, 2014 a 2016
title_full_unstemmed Análise do Sistema de Informação da Vigilância de Eventos Adversos Pós-Vacinação no Brasil, 2014 a 2016
title_short Análise do Sistema de Informação da Vigilância de Eventos Adversos Pós-Vacinação no Brasil, 2014 a 2016
title_sort análise do sistema de informação da vigilância de eventos adversos pós-vacinação no brasil, 2014 a 2016
topic Artigo Original
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385780/
https://www.ncbi.nlm.nih.gov/pubmed/31093041
http://dx.doi.org/10.26633/RPSP.2018.12
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