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The SUMO-Conjugase Ubc9 Prevents the Degradation of the Dopamine Transporter, Enhancing Its Cell Surface Level and Dopamine Uptake

The dopamine transporter (DAT) is a plasma membrane protein responsible for the uptake of released dopamine back to the presynaptic terminal and ending dopamine neurotransmission. The DAT is the molecular target for cocaine and amphetamine as well as a number of pathological conditions including aut...

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Detalles Bibliográficos
Autores principales: Cartier, Etienne, Garcia-Olivares, Jennie, Janezic, Eric, Viana, Juan, Moore, Michael, Lin, Min Landon, Caplan, Jeffrey L., Torres, Gonzalo, Kim, Yong-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386010/
https://www.ncbi.nlm.nih.gov/pubmed/30828290
http://dx.doi.org/10.3389/fncel.2019.00035