Cargando…
The SUMO-Conjugase Ubc9 Prevents the Degradation of the Dopamine Transporter, Enhancing Its Cell Surface Level and Dopamine Uptake
The dopamine transporter (DAT) is a plasma membrane protein responsible for the uptake of released dopamine back to the presynaptic terminal and ending dopamine neurotransmission. The DAT is the molecular target for cocaine and amphetamine as well as a number of pathological conditions including aut...
Autores principales: | Cartier, Etienne, Garcia-Olivares, Jennie, Janezic, Eric, Viana, Juan, Moore, Michael, Lin, Min Landon, Caplan, Jeffrey L., Torres, Gonzalo, Kim, Yong-Hwan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386010/ https://www.ncbi.nlm.nih.gov/pubmed/30828290 http://dx.doi.org/10.3389/fncel.2019.00035 |
Ejemplares similares
-
The SUMO Conjugase Ubc9 Protects Dopaminergic Cells from Cytotoxicity and Enhances the Stability of α-Synuclein in Parkinson’s Disease Models
por: Verma, Dinesh Kumar, et al.
Publicado: (2020) -
The metabolite-controlled ubiquitin conjugase Ubc8 promotes mitochondrial protein import
por: Rödl, Saskia, et al.
Publicado: (2022) -
The dopamine transporter antiports potassium to increase the uptake of dopamine
por: Schmidt, Solveig G., et al.
Publicado: (2022) -
Inhibition of Dopamine Transporter Activity by G Protein βγ Subunits
por: Garcia-Olivares, Jennie, et al.
Publicado: (2013) -
Role of Ubiquitin Ligases and Conjugases in Targeted Cancer Therapy
por: Vriend, Jerry
Publicado: (2023)