De novo gene signature identification from single‐cell RNA‐seq with hierarchical Poisson factorization

Common approaches to gene signature discovery in single‐cell RNA‐sequencing (scRNA‐seq) depend upon predefined structures like clusters or pseudo‐temporal order, require prior normalization, or do not account for the sparsity of single‐cell data. We present single‐cell hierarchical Poisson factoriza...

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Detalles Bibliográficos
Autores principales: Levitin, Hanna Mendes, Yuan, Jinzhou, Cheng, Yim Ling, Ruiz, Francisco JR, Bush, Erin C, Bruce, Jeffrey N, Canoll, Peter, Iavarone, Antonio, Lasorella, Anna, Blei, David M, Sims, Peter A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386217/
https://www.ncbi.nlm.nih.gov/pubmed/30796088
http://dx.doi.org/10.15252/msb.20188557

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