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Role of deformable cancer cells on wall shear stress-associated-VEGF secretion by endothelium in microvasculature
Endothelial surface layer (glycocalyx) is the major physiological regulator of tumor cell adhesion to endothelium. Cancer cells express vascular endothelial growth factor (VEGF) which increases the permeability of a microvessel wall by degrading glycocalyx. Endothelial cells lining large arteries ha...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386247/ https://www.ncbi.nlm.nih.gov/pubmed/30794550 http://dx.doi.org/10.1371/journal.pone.0211418 |