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Growth arrest and DNA damage 45γ is required for caspase-dependent renal tubular cell apoptosis

BACKGROUND: Growth Arrest and DNA Damage 45γ (GADD45γ) is a member of the DNA damage-inducible gene family which responds to environmental stresses. Apoptosis is a critical mode of renal tubular cell death in nephrotoxin-induced acute kidney injury. In this study, we investigated the role of GADD45γ...

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Detalles Bibliográficos
Autores principales: Shin, Gyu-Tae, Lee, Hwa Joung, Park, Ji Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386268/
https://www.ncbi.nlm.nih.gov/pubmed/30794682
http://dx.doi.org/10.1371/journal.pone.0212818

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