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Cigarette smoke extracts and cadmium induce COX-2 expression through γ-secretase-mediated p38 MAPK activation in C6 astroglia cells
Exposure to cigarette smoke has been implicated in the progression of cerebrovascular and neurological disorders like stroke through inflammation and blood-brain barrier disruption. In this study, we investigated the signaling cascade activated by cigarette smoke extracts (CSE) and cadmium (Cd) resu...
Autores principales: | Lim, Hyun Joung, Park, Jung Hyun, Jo, Chulman, Yoon, Keejung, Koh, Young Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386363/ https://www.ncbi.nlm.nih.gov/pubmed/30794693 http://dx.doi.org/10.1371/journal.pone.0212749 |
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