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Cell geometry determines symmetric and asymmetric division plane selection in Arabidopsis early embryos
Plant tissue architecture and organ morphogenesis rely on the proper orientation of cell divisions. Previous attempts to predict division planes from cell geometry in plants mostly focused on 2D symmetric divisions. Using the stereotyped division patterns of Arabidopsis thaliana early embryogenesis,...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386405/ https://www.ncbi.nlm.nih.gov/pubmed/30742612 http://dx.doi.org/10.1371/journal.pcbi.1006771 |
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author | Moukhtar, Julien Trubuil, Alain Belcram, Katia Legland, David Khadir, Zhor Urbain, Aurélie Palauqui, Jean-Christophe Andrey, Philippe |
author_facet | Moukhtar, Julien Trubuil, Alain Belcram, Katia Legland, David Khadir, Zhor Urbain, Aurélie Palauqui, Jean-Christophe Andrey, Philippe |
author_sort | Moukhtar, Julien |
collection | PubMed |
description | Plant tissue architecture and organ morphogenesis rely on the proper orientation of cell divisions. Previous attempts to predict division planes from cell geometry in plants mostly focused on 2D symmetric divisions. Using the stereotyped division patterns of Arabidopsis thaliana early embryogenesis, we investigated geometrical principles underlying plane selection in symmetric and in asymmetric divisions within complex 3D cell shapes. Introducing a 3D computational model of cell division, we show that area minimization constrained on passing through the cell centroid predicts observed divisions. Our results suggest that the positioning of division planes ensues from cell geometry and gives rise to spatially organized cell types with stereotyped shapes, thus underlining the role of self-organization in the developing architecture of the embryo. Our data further suggested the rule could be interpreted as surface minimization constrained by the nucleus position, which was validated using live imaging of cell divisions in the stomatal cell lineage. |
format | Online Article Text |
id | pubmed-6386405 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-63864052019-03-08 Cell geometry determines symmetric and asymmetric division plane selection in Arabidopsis early embryos Moukhtar, Julien Trubuil, Alain Belcram, Katia Legland, David Khadir, Zhor Urbain, Aurélie Palauqui, Jean-Christophe Andrey, Philippe PLoS Comput Biol Research Article Plant tissue architecture and organ morphogenesis rely on the proper orientation of cell divisions. Previous attempts to predict division planes from cell geometry in plants mostly focused on 2D symmetric divisions. Using the stereotyped division patterns of Arabidopsis thaliana early embryogenesis, we investigated geometrical principles underlying plane selection in symmetric and in asymmetric divisions within complex 3D cell shapes. Introducing a 3D computational model of cell division, we show that area minimization constrained on passing through the cell centroid predicts observed divisions. Our results suggest that the positioning of division planes ensues from cell geometry and gives rise to spatially organized cell types with stereotyped shapes, thus underlining the role of self-organization in the developing architecture of the embryo. Our data further suggested the rule could be interpreted as surface minimization constrained by the nucleus position, which was validated using live imaging of cell divisions in the stomatal cell lineage. Public Library of Science 2019-02-11 /pmc/articles/PMC6386405/ /pubmed/30742612 http://dx.doi.org/10.1371/journal.pcbi.1006771 Text en © 2019 Moukhtar et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Moukhtar, Julien Trubuil, Alain Belcram, Katia Legland, David Khadir, Zhor Urbain, Aurélie Palauqui, Jean-Christophe Andrey, Philippe Cell geometry determines symmetric and asymmetric division plane selection in Arabidopsis early embryos |
title | Cell geometry determines symmetric and asymmetric division plane selection in Arabidopsis early embryos |
title_full | Cell geometry determines symmetric and asymmetric division plane selection in Arabidopsis early embryos |
title_fullStr | Cell geometry determines symmetric and asymmetric division plane selection in Arabidopsis early embryos |
title_full_unstemmed | Cell geometry determines symmetric and asymmetric division plane selection in Arabidopsis early embryos |
title_short | Cell geometry determines symmetric and asymmetric division plane selection in Arabidopsis early embryos |
title_sort | cell geometry determines symmetric and asymmetric division plane selection in arabidopsis early embryos |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386405/ https://www.ncbi.nlm.nih.gov/pubmed/30742612 http://dx.doi.org/10.1371/journal.pcbi.1006771 |
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