The switch between acute and persistent paramyxovirus infection caused by single amino acid substitutions in the RNA polymerase P subunit

Paramyxoviruses can establish persistent infections both in vitro and in vivo, some of which lead to chronic disease. However, little is known about the molecular events that contribute to the establishment of persistent infections by RNA viruses. Using parainfluenza virus type 5 (PIV5) as a model w...

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Detalles Bibliográficos
Autores principales: Young, Dan F., Wignall-Fleming, Elizabeth B., Busse, David C., Pickin, Matthew J., Hankinson, Jack, Randall, Elizabeth M., Tavendale, Amy, Davison, Andrew J., Lamont, Douglas, Tregoning, John S., Goodbourn, Steve, Randall, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386407/
https://www.ncbi.nlm.nih.gov/pubmed/30742688
http://dx.doi.org/10.1371/journal.ppat.1007561

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