Cargando…
CRISPR-cas gene-editing as plausible treatment of neuromuscular and nucleotide-repeat-expansion diseases: A systematic review
INTRODUCTION: The system of clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated proteins (cas) is a new technology that allows easier manipulation of the genome. Its potential to edit genes opened a new door in treatment development for incurable neurological mon...
Autores principales: | Babačić, Haris, Mehta, Aditi, Merkel, Olivia, Schoser, Benedikt |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386526/ https://www.ncbi.nlm.nih.gov/pubmed/30794581 http://dx.doi.org/10.1371/journal.pone.0212198 |
Ejemplares similares
-
Optimizing CRISPR/Cas9 Editing of Repetitive Single Nucleotide Variants
por: Usher, Inga, et al.
Publicado: (2022) -
Antisense Transcription across Nucleotide Repeat Expansions in Neurodegenerative and Neuromuscular Diseases: Progress and Mysteries
por: Castro, Ana F., et al.
Publicado: (2020) -
Efficient CRISPR/Cas9-mediated editing of trinucleotide repeat expansion in myotonic dystrophy patient-derived iPS and myogenic cells
por: Dastidar, Sumitava, et al.
Publicado: (2018) -
Effective CRISPR/Cas9-based nucleotide editing in zebrafish to model human genetic cardiovascular disorders
por: Tessadori, Federico, et al.
Publicado: (2018) -
CRISPR-Cas9 DNA Base-Editing and Prime-Editing
por: Kantor, Ariel, et al.
Publicado: (2020)