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A Novel, Multiple-Antigen Pneumococcal Vaccine Protects against Lethal Streptococcus pneumoniae Challenge

Current vaccination against Streptococcus pneumoniae uses vaccines based on capsular polysaccharides from selected serotypes and has led to nonvaccine serotype replacement disease. We have investigated an alternative serotype-independent approach, using multiple-antigen vaccines (MAV) prepared from...

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Detalles Bibliográficos
Autores principales: Chan, Win-Yan, Entwisle, Claire, Ercoli, Giuseppe, Ramos-Sevillano, Elise, McIlgorm, Ann, Cecchini, Paola, Bailey, Christopher, Lam, Oliver, Whiting, Gail, Green, Nicola, Goldblatt, David, Wheeler, Jun X., Brown, Jeremy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386546/
https://www.ncbi.nlm.nih.gov/pubmed/30530620
http://dx.doi.org/10.1128/IAI.00846-18