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A Novel, Multiple-Antigen Pneumococcal Vaccine Protects against Lethal Streptococcus pneumoniae Challenge
Current vaccination against Streptococcus pneumoniae uses vaccines based on capsular polysaccharides from selected serotypes and has led to nonvaccine serotype replacement disease. We have investigated an alternative serotype-independent approach, using multiple-antigen vaccines (MAV) prepared from...
Autores principales: | Chan, Win-Yan, Entwisle, Claire, Ercoli, Giuseppe, Ramos-Sevillano, Elise, McIlgorm, Ann, Cecchini, Paola, Bailey, Christopher, Lam, Oliver, Whiting, Gail, Green, Nicola, Goldblatt, David, Wheeler, Jun X., Brown, Jeremy S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386546/ https://www.ncbi.nlm.nih.gov/pubmed/30530620 http://dx.doi.org/10.1128/IAI.00846-18 |
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