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Most viral peptides displayed by class I MHC on infected cells are immunogenic

CD8(+) T cells are essential effectors in antiviral immunity, recognizing short virus-derived peptides presented by MHC class I (pMHCI) on the surface of infected cells. However, the fraction of viral pMHCI on infected cells that are immunogenic has not been shown for any virus. To approach this fun...

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Detalles Bibliográficos
Autores principales:	Croft, Nathan P., Smith, Stewart A., Pickering, Jana, Sidney, John, Peters, Bjoern, Faridi, Pouya, Witney, Matthew J., Sebastian, Prince, Flesch, Inge E. A., Heading, Sally L., Sette, Alessandro, La Gruta, Nicole L., Purcell, Anthony W., Tscharke, David C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2019
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386720/ https://www.ncbi.nlm.nih.gov/pubmed/30718433 http://dx.doi.org/10.1073/pnas.1815239116

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