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Alleles of Insm1 determine whether RIP1-Tag2 mice produce insulinomas or nonfunctioning pancreatic neuroendocrine tumors

The two most common types of pancreatic neuroendocrine tumors (PanNETs) are insulinomas and nonfunctioning PanNETs (NF-PanNETs). Insulinomas are small, rarely metastatic tumors that secrete high amounts of insulin, and nonfunctioning PanNETs are larger tumors that are frequently metastatic but that...

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Detalles Bibliográficos
Autores principales:	Kobayashi, Shinta, Contractor, Tanupriya, Vosburgh, Evan, Du, Yi-Chieh Nancy, Tang, Laura H., Clausen, Richard, Harris, Chris R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386750/ https://www.ncbi.nlm.nih.gov/pubmed/30796198 http://dx.doi.org/10.1038/s41389-019-0127-1

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