Morphing of Ibogaine: A Successful Attempt into the Search for Sigma-2 Receptor Ligands

Ibogaine is a psychoactive indole alkaloid with high affinity for several targets including the σ(2) receptor. Indeed, extensive data support the involvement of the σ(2) receptor in neurological disorders, including Alzheimer’s disease, schizophrenia, alcohol abuse and pain. Due to its serious side...

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Detalles Bibliográficos
Autores principales: Floresta, Giuseppe, Dichiara, Maria, Gentile, Davide, Prezzavento, Orazio, Marrazzo, Agostino, Rescifina, Antonio, Amata, Emanuele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386901/
https://www.ncbi.nlm.nih.gov/pubmed/30678129
http://dx.doi.org/10.3390/ijms20030488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386901/
https://www.ncbi.nlm.nih.gov/pubmed/30678129
http://dx.doi.org/10.3390/ijms20030488

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