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Morphing of Ibogaine: A Successful Attempt into the Search for Sigma-2 Receptor Ligands
Ibogaine is a psychoactive indole alkaloid with high affinity for several targets including the σ(2) receptor. Indeed, extensive data support the involvement of the σ(2) receptor in neurological disorders, including Alzheimer’s disease, schizophrenia, alcohol abuse and pain. Due to its serious side...
Autores principales: | Floresta, Giuseppe, Dichiara, Maria, Gentile, Davide, Prezzavento, Orazio, Marrazzo, Agostino, Rescifina, Antonio, Amata, Emanuele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386901/ https://www.ncbi.nlm.nih.gov/pubmed/30678129 http://dx.doi.org/10.3390/ijms20030488 |
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