The Possible Role of Complete Loss of Myostatin in Limiting Excessive Proliferation of Muscle Cells (C2C12) via Activation of MicroRNAs

Myostatin (MSTN) is a member of the TGF-β superfamily that negatively regulates skeletal muscle growth and differentiation. However, the mechanism by which complete MSTN deletion limits excessive proliferation of muscle cells remains unclear. In this study, we knocked out MSTN in mouse myoblast line...

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Detalles Bibliográficos
Autores principales: Huang, Peixuan, Pang, Daxin, Wang, Kankan, Xu, Aishi, Yao, Chaogang, Li, Mengjing, You, Wenni, Wang, Qiushuang, Yu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386905/
https://www.ncbi.nlm.nih.gov/pubmed/30717351
http://dx.doi.org/10.3390/ijms20030643

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