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A Flexible Platform of Electrochemically Functionalized Carbon Nanotubes for NADH Sensors
A flexible electrode system entirely constituted by single-walled carbon nanotubes (SWCNTs) has been proposed as the sensor platform for β-nicotinamide adenine dinucleotide (NADH) detection. The performance of the device, in terms of potential at which the electrochemical process takes place, signif...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386930/ https://www.ncbi.nlm.nih.gov/pubmed/30691171 http://dx.doi.org/10.3390/s19030518 |
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author | Heras, Aranzazu Vulcano, Fabio Garoz-Ruiz, Jesus Porcelli, Nicola Terzi, Fabio Colina, Alvaro Seeber, Renato Zanardi, Chiara |
author_facet | Heras, Aranzazu Vulcano, Fabio Garoz-Ruiz, Jesus Porcelli, Nicola Terzi, Fabio Colina, Alvaro Seeber, Renato Zanardi, Chiara |
author_sort | Heras, Aranzazu |
collection | PubMed |
description | A flexible electrode system entirely constituted by single-walled carbon nanotubes (SWCNTs) has been proposed as the sensor platform for β-nicotinamide adenine dinucleotide (NADH) detection. The performance of the device, in terms of potential at which the electrochemical process takes place, significantly improves by electrochemical functionalization of the carbon-based material with a molecule possessing an o-hydroquinone residue, namely caffeic acid. Both the processes of SWCNT functionalization and NADH detection have been studied by combining electrochemical and spectroelectrochemical experiments, in order to achieve direct evidence of the electrode modification by the organic residues and to study the electrocatalytic activity of the resulting material in respect to functional groups present at the electrode/solution interface. Electrochemical measurements performed at the fixed potential of +0.30 V let us envision the possible use of the device as an amperometric sensor for NADH detection. Spectroelectrochemistry also demonstrates the effectiveness of the device in acting as a voltabsorptometric sensor for the detection of this same analyte by exploiting this different transduction mechanism, potentially less prone to the possible presence of interfering species. |
format | Online Article Text |
id | pubmed-6386930 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-63869302019-02-26 A Flexible Platform of Electrochemically Functionalized Carbon Nanotubes for NADH Sensors Heras, Aranzazu Vulcano, Fabio Garoz-Ruiz, Jesus Porcelli, Nicola Terzi, Fabio Colina, Alvaro Seeber, Renato Zanardi, Chiara Sensors (Basel) Article A flexible electrode system entirely constituted by single-walled carbon nanotubes (SWCNTs) has been proposed as the sensor platform for β-nicotinamide adenine dinucleotide (NADH) detection. The performance of the device, in terms of potential at which the electrochemical process takes place, significantly improves by electrochemical functionalization of the carbon-based material with a molecule possessing an o-hydroquinone residue, namely caffeic acid. Both the processes of SWCNT functionalization and NADH detection have been studied by combining electrochemical and spectroelectrochemical experiments, in order to achieve direct evidence of the electrode modification by the organic residues and to study the electrocatalytic activity of the resulting material in respect to functional groups present at the electrode/solution interface. Electrochemical measurements performed at the fixed potential of +0.30 V let us envision the possible use of the device as an amperometric sensor for NADH detection. Spectroelectrochemistry also demonstrates the effectiveness of the device in acting as a voltabsorptometric sensor for the detection of this same analyte by exploiting this different transduction mechanism, potentially less prone to the possible presence of interfering species. MDPI 2019-01-26 /pmc/articles/PMC6386930/ /pubmed/30691171 http://dx.doi.org/10.3390/s19030518 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Heras, Aranzazu Vulcano, Fabio Garoz-Ruiz, Jesus Porcelli, Nicola Terzi, Fabio Colina, Alvaro Seeber, Renato Zanardi, Chiara A Flexible Platform of Electrochemically Functionalized Carbon Nanotubes for NADH Sensors |
title | A Flexible Platform of Electrochemically Functionalized Carbon Nanotubes for NADH Sensors |
title_full | A Flexible Platform of Electrochemically Functionalized Carbon Nanotubes for NADH Sensors |
title_fullStr | A Flexible Platform of Electrochemically Functionalized Carbon Nanotubes for NADH Sensors |
title_full_unstemmed | A Flexible Platform of Electrochemically Functionalized Carbon Nanotubes for NADH Sensors |
title_short | A Flexible Platform of Electrochemically Functionalized Carbon Nanotubes for NADH Sensors |
title_sort | flexible platform of electrochemically functionalized carbon nanotubes for nadh sensors |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386930/ https://www.ncbi.nlm.nih.gov/pubmed/30691171 http://dx.doi.org/10.3390/s19030518 |
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