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A Flexible Platform of Electrochemically Functionalized Carbon Nanotubes for NADH Sensors

A flexible electrode system entirely constituted by single-walled carbon nanotubes (SWCNTs) has been proposed as the sensor platform for β-nicotinamide adenine dinucleotide (NADH) detection. The performance of the device, in terms of potential at which the electrochemical process takes place, signif...

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Autores principales: Heras, Aranzazu, Vulcano, Fabio, Garoz-Ruiz, Jesus, Porcelli, Nicola, Terzi, Fabio, Colina, Alvaro, Seeber, Renato, Zanardi, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386930/
https://www.ncbi.nlm.nih.gov/pubmed/30691171
http://dx.doi.org/10.3390/s19030518
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author Heras, Aranzazu
Vulcano, Fabio
Garoz-Ruiz, Jesus
Porcelli, Nicola
Terzi, Fabio
Colina, Alvaro
Seeber, Renato
Zanardi, Chiara
author_facet Heras, Aranzazu
Vulcano, Fabio
Garoz-Ruiz, Jesus
Porcelli, Nicola
Terzi, Fabio
Colina, Alvaro
Seeber, Renato
Zanardi, Chiara
author_sort Heras, Aranzazu
collection PubMed
description A flexible electrode system entirely constituted by single-walled carbon nanotubes (SWCNTs) has been proposed as the sensor platform for β-nicotinamide adenine dinucleotide (NADH) detection. The performance of the device, in terms of potential at which the electrochemical process takes place, significantly improves by electrochemical functionalization of the carbon-based material with a molecule possessing an o-hydroquinone residue, namely caffeic acid. Both the processes of SWCNT functionalization and NADH detection have been studied by combining electrochemical and spectroelectrochemical experiments, in order to achieve direct evidence of the electrode modification by the organic residues and to study the electrocatalytic activity of the resulting material in respect to functional groups present at the electrode/solution interface. Electrochemical measurements performed at the fixed potential of +0.30 V let us envision the possible use of the device as an amperometric sensor for NADH detection. Spectroelectrochemistry also demonstrates the effectiveness of the device in acting as a voltabsorptometric sensor for the detection of this same analyte by exploiting this different transduction mechanism, potentially less prone to the possible presence of interfering species.
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spelling pubmed-63869302019-02-26 A Flexible Platform of Electrochemically Functionalized Carbon Nanotubes for NADH Sensors Heras, Aranzazu Vulcano, Fabio Garoz-Ruiz, Jesus Porcelli, Nicola Terzi, Fabio Colina, Alvaro Seeber, Renato Zanardi, Chiara Sensors (Basel) Article A flexible electrode system entirely constituted by single-walled carbon nanotubes (SWCNTs) has been proposed as the sensor platform for β-nicotinamide adenine dinucleotide (NADH) detection. The performance of the device, in terms of potential at which the electrochemical process takes place, significantly improves by electrochemical functionalization of the carbon-based material with a molecule possessing an o-hydroquinone residue, namely caffeic acid. Both the processes of SWCNT functionalization and NADH detection have been studied by combining electrochemical and spectroelectrochemical experiments, in order to achieve direct evidence of the electrode modification by the organic residues and to study the electrocatalytic activity of the resulting material in respect to functional groups present at the electrode/solution interface. Electrochemical measurements performed at the fixed potential of +0.30 V let us envision the possible use of the device as an amperometric sensor for NADH detection. Spectroelectrochemistry also demonstrates the effectiveness of the device in acting as a voltabsorptometric sensor for the detection of this same analyte by exploiting this different transduction mechanism, potentially less prone to the possible presence of interfering species. MDPI 2019-01-26 /pmc/articles/PMC6386930/ /pubmed/30691171 http://dx.doi.org/10.3390/s19030518 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Heras, Aranzazu
Vulcano, Fabio
Garoz-Ruiz, Jesus
Porcelli, Nicola
Terzi, Fabio
Colina, Alvaro
Seeber, Renato
Zanardi, Chiara
A Flexible Platform of Electrochemically Functionalized Carbon Nanotubes for NADH Sensors
title A Flexible Platform of Electrochemically Functionalized Carbon Nanotubes for NADH Sensors
title_full A Flexible Platform of Electrochemically Functionalized Carbon Nanotubes for NADH Sensors
title_fullStr A Flexible Platform of Electrochemically Functionalized Carbon Nanotubes for NADH Sensors
title_full_unstemmed A Flexible Platform of Electrochemically Functionalized Carbon Nanotubes for NADH Sensors
title_short A Flexible Platform of Electrochemically Functionalized Carbon Nanotubes for NADH Sensors
title_sort flexible platform of electrochemically functionalized carbon nanotubes for nadh sensors
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386930/
https://www.ncbi.nlm.nih.gov/pubmed/30691171
http://dx.doi.org/10.3390/s19030518
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