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Discovery of New Cyclopentaquinoline Analogues as Multifunctional Agents for the Treatment of Alzheimer’s Disease
Here we report the two-step synthesis of 8 new cyclopentaquinoline derivatives as modifications of the tetrahydroacridine structure. Next, the biological assessment of each of them was performed. Based on the obtained results we identified 6-chloro-N-[2-(2,3-dihydro-1H-cyclopenta[b]quinolin-9-ylamin...
Autores principales: | Czarnecka, Kamila, Girek, Małgorzata, Kręcisz, Paweł, Skibiński, Robert, Łątka, Kamil, Jończyk, Jakub, Bajda, Marek, Kabziński, Jacek, Majsterek, Ireneusz, Szymczyk, Piotr, Szymański, Paweł |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386991/ https://www.ncbi.nlm.nih.gov/pubmed/30678364 http://dx.doi.org/10.3390/ijms20030498 |
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