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Dynamic Characterization of the Human Heme Nitric Oxide/Oxygen (HNOX) Domain under the Influence of Diatomic Gaseous Ligands

Soluble guanylate cyclase (sGC) regulates numerous physiological processes. The β subunit Heme Nitric Oxide/Oxygen (HNOX) domain makes this protein sensitive to small gaseous ligands. The structural basis of the activation mechanism of sGC under the influence of ligands (NO, O(2), CO) is poorly unde...

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Detalles Bibliográficos
Autores principales:	Khalid, Rana Rehan, Siddiqi, Abdul Rauf, Mylonas, Efstratios, Maryam, Arooma, Kokkinidis, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387030/ https://www.ncbi.nlm.nih.gov/pubmed/30736292 http://dx.doi.org/10.3390/ijms20030698

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