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A Non-Invasive Medical Device for Parkinson’s Patients with Episodes of Freezing of Gait †

A critical symptom of Parkinson’s disease (PD) is the occurrence of Freezing of Gait (FOG), an episodic disorder that causes frequent falls and consequential injuries in PD patients. There are various auditory, visual, tactile, and other types of stimulation interventions that can be used to induce...

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Autores principales: Punin, Catalina, Barzallo, Boris, Clotet, Roger, Bermeo, Alexander, Bravo, Marco, Bermeo, Juan Pablo, Llumiguano, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387047/
https://www.ncbi.nlm.nih.gov/pubmed/30759789
http://dx.doi.org/10.3390/s19030737
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author Punin, Catalina
Barzallo, Boris
Clotet, Roger
Bermeo, Alexander
Bravo, Marco
Bermeo, Juan Pablo
Llumiguano, Carlos
author_facet Punin, Catalina
Barzallo, Boris
Clotet, Roger
Bermeo, Alexander
Bravo, Marco
Bermeo, Juan Pablo
Llumiguano, Carlos
author_sort Punin, Catalina
collection PubMed
description A critical symptom of Parkinson’s disease (PD) is the occurrence of Freezing of Gait (FOG), an episodic disorder that causes frequent falls and consequential injuries in PD patients. There are various auditory, visual, tactile, and other types of stimulation interventions that can be used to induce PD patients to escape FOG episodes. In this article, we describe a low cost wearable system for non-invasive gait monitoring and external delivery of superficial vibratory stimulation to the lower extremities triggered by FOG episodes. The intended purpose is to reduce the duration of the FOG episode, thus allowing prompt resumption of gait to prevent major injuries. The system, based on an Android mobile application, uses a tri-axial accelerometer device for gait data acquisition. Gathered data is processed via a discrete wavelet transform-based algorithm that precisely detects FOG episodes in real time. Detection activates external vibratory stimulation of the legs to reduce FOG time. The integration of detection and stimulation in one low cost device is the chief novel contribution of this work. We present analyses of sensitivity, specificity and effectiveness of the proposed system to validate its usefulness.
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spelling pubmed-63870472019-02-26 A Non-Invasive Medical Device for Parkinson’s Patients with Episodes of Freezing of Gait † Punin, Catalina Barzallo, Boris Clotet, Roger Bermeo, Alexander Bravo, Marco Bermeo, Juan Pablo Llumiguano, Carlos Sensors (Basel) Article A critical symptom of Parkinson’s disease (PD) is the occurrence of Freezing of Gait (FOG), an episodic disorder that causes frequent falls and consequential injuries in PD patients. There are various auditory, visual, tactile, and other types of stimulation interventions that can be used to induce PD patients to escape FOG episodes. In this article, we describe a low cost wearable system for non-invasive gait monitoring and external delivery of superficial vibratory stimulation to the lower extremities triggered by FOG episodes. The intended purpose is to reduce the duration of the FOG episode, thus allowing prompt resumption of gait to prevent major injuries. The system, based on an Android mobile application, uses a tri-axial accelerometer device for gait data acquisition. Gathered data is processed via a discrete wavelet transform-based algorithm that precisely detects FOG episodes in real time. Detection activates external vibratory stimulation of the legs to reduce FOG time. The integration of detection and stimulation in one low cost device is the chief novel contribution of this work. We present analyses of sensitivity, specificity and effectiveness of the proposed system to validate its usefulness. MDPI 2019-02-12 /pmc/articles/PMC6387047/ /pubmed/30759789 http://dx.doi.org/10.3390/s19030737 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Punin, Catalina
Barzallo, Boris
Clotet, Roger
Bermeo, Alexander
Bravo, Marco
Bermeo, Juan Pablo
Llumiguano, Carlos
A Non-Invasive Medical Device for Parkinson’s Patients with Episodes of Freezing of Gait †
title A Non-Invasive Medical Device for Parkinson’s Patients with Episodes of Freezing of Gait †
title_full A Non-Invasive Medical Device for Parkinson’s Patients with Episodes of Freezing of Gait †
title_fullStr A Non-Invasive Medical Device for Parkinson’s Patients with Episodes of Freezing of Gait †
title_full_unstemmed A Non-Invasive Medical Device for Parkinson’s Patients with Episodes of Freezing of Gait †
title_short A Non-Invasive Medical Device for Parkinson’s Patients with Episodes of Freezing of Gait †
title_sort non-invasive medical device for parkinson’s patients with episodes of freezing of gait †
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387047/
https://www.ncbi.nlm.nih.gov/pubmed/30759789
http://dx.doi.org/10.3390/s19030737
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