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Optimization of Early Steps in Oncolytic Adenovirus ONCOS-401 Production in T-175 and HYPERFlasks

Oncolytic adenoviruses can trigger lysis of tumor cells, induce an antitumor immune response, bypass classical chemotherapeutic resistance strategies of tumors, and provide opportunities for combination strategies. A major challenge is the development of scalable production methods for viral seed st...

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Detalles Bibliográficos
Autores principales: Kuryk, Lukasz, Møller, Anne-Sophie W, Vuolanto, Antti, Pesonen, Sari, Garofalo, Mariangela, Cerullo, Vincenzo, Jaderberg, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387112/
https://www.ncbi.nlm.nih.gov/pubmed/30709038
http://dx.doi.org/10.3390/ijms20030621

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