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Quantifying BRCA1 and BRCA2 mRNA Isoform Expression Levels in Single Cells

BRCA1 and BRCA2 spliceogenic variants are often associated with an elevated risk of breast and ovarian cancers. Analyses of BRCA1 and BRCA2 splicing patterns have traditionally used technologies that sample a population of cells but do not account for the variation that may be present between indivi...

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Detalles Bibliográficos
Autores principales: Lattimore, Vanessa L., Pearson, John F., Morley-Bunker, Arthur E., Investigators, kConFab, Spurdle, Amanda B., Robinson, Bridget A., Currie, Margaret J., Walker, Logan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387195/
https://www.ncbi.nlm.nih.gov/pubmed/30736279
http://dx.doi.org/10.3390/ijms20030693