Cargando…
Quantifying BRCA1 and BRCA2 mRNA Isoform Expression Levels in Single Cells
BRCA1 and BRCA2 spliceogenic variants are often associated with an elevated risk of breast and ovarian cancers. Analyses of BRCA1 and BRCA2 splicing patterns have traditionally used technologies that sample a population of cells but do not account for the variation that may be present between indivi...
Autores principales: | Lattimore, Vanessa L., Pearson, John F., Morley-Bunker, Arthur E., Investigators, kConFab, Spurdle, Amanda B., Robinson, Bridget A., Currie, Margaret J., Walker, Logan C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387195/ https://www.ncbi.nlm.nih.gov/pubmed/30736279 http://dx.doi.org/10.3390/ijms20030693 |
Ejemplares similares
-
Use of DNA–Damaging Agents and RNA Pooling to Assess Expression Profiles Associated with BRCA1 and BRCA2 Mutation Status in Familial Breast Cancer Patients
por: Walker, Logan C., et al.
Publicado: (2010) -
Investigation of Experimental Factors That Underlie BRCA1/2 mRNA Isoform Expression Variation: Recommendations for Utilizing Targeted RNA Sequencing to Evaluate Potential Spliceogenic Variants
por: Lattimore, Vanessa L., et al.
Publicado: (2018) -
BRCA1 and BRCA2 Missense Variants of High and Low Clinical Significance Influence Lymphoblastoid Cell Line Post-Irradiation Gene Expression
por: Waddell, Nic, et al.
Publicado: (2008) -
Genotypic and phenotypic analysis of familial male breast cancer shows under representation of the HER2 and basal subtypes in BRCA-associated carcinomas
por: Deb, Siddhartha, et al.
Publicado: (2012) -
Prostate screening uptake in Australian BRCA1 and BRCA2 carriers
por: McKinley, Joanne M, et al.
Publicado: (2007)