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Energy-Dependent Endocytosis Is Involved in the Absorption of Indomethacin Nanoparticles in the Small Intestine

We previously reported that oral formulations containing indomethacin nanoparticles (IND-NPs) showed high bioavailability, and, consequently, improved therapeutic effects and reduced injury to the small intestine. However, the pathway for the transintestinal penetration of nanoparticles remained unc...

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Detalles Bibliográficos
Autores principales: Ishii, Miyu, Fukuoka, Yuya, Deguchi, Saori, Otake, Hiroko, Tanino, Tadatoshi, Nagai, Noriaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387232/
https://www.ncbi.nlm.nih.gov/pubmed/30678310
http://dx.doi.org/10.3390/ijms20030476