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Energy-Dependent Endocytosis Is Involved in the Absorption of Indomethacin Nanoparticles in the Small Intestine
We previously reported that oral formulations containing indomethacin nanoparticles (IND-NPs) showed high bioavailability, and, consequently, improved therapeutic effects and reduced injury to the small intestine. However, the pathway for the transintestinal penetration of nanoparticles remained unc...
Autores principales: | Ishii, Miyu, Fukuoka, Yuya, Deguchi, Saori, Otake, Hiroko, Tanino, Tadatoshi, Nagai, Noriaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387232/ https://www.ncbi.nlm.nih.gov/pubmed/30678310 http://dx.doi.org/10.3390/ijms20030476 |
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