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Multi-Spectroscopic Characterization of Human Serum Albumin Binding with Cyclobenzaprine Hydrochloride: Insights from Biophysical and In Silico Approaches

Cyclobenzaprine hydrochloride (CBH) is a well-known muscle relaxant that is widely used to relieve muscle spasms and other pain associated with acute musculoskeletal conditions. In this study, we elucidated the binding characteristics of this muscle relaxant to human serum albumin (HSA). From a phar...

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Detalles Bibliográficos
Autores principales: Baig, Mohammad Hassan, Rahman, Safikur, Rabbani, Gulam, Imran, Mohd, Ahmad, Khurshid, Choi, Inho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387470/
https://www.ncbi.nlm.nih.gov/pubmed/30717459
http://dx.doi.org/10.3390/ijms20030662