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Synthesis of budesonide conjugates and their anti-inflammatory effects: a preliminary study

PURPOSE: Budesonide (Bud) is a nonhalogenated glucocorticoid with high anti-inflammatory potency and low systemic side effects. However, the poor water solubility of Bud affects its dissolution and release behavior, thus influencing its anti-inflammatory effect. This study was aimed at synthesizing...

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Detalles Bibliográficos
Autores principales: Yan, Yan, Wang, Pengchong, Li, Ruiying, Sun, Ying, Zhang, Rui, Huo, Chuanchuan, Xing, Jianfeng, Dong, Yalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387599/
https://www.ncbi.nlm.nih.gov/pubmed/30858698
http://dx.doi.org/10.2147/DDDT.S192348