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Monosialoganglioside protects against bupivacaine-induced neurotoxicity caused by endoplasmic reticulum stress in rats

BACKGROUND: Local anesthetics in spinal anesthesia have neurotoxic effects, resulting in severe neurological complications. Intrathecal monosialoganglioside (GM1) administration has a therapeutic effect on bupivacaine-induced neurotoxicity. The aim of this study was to determine the underlying mecha...

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Detalles Bibliográficos
Autores principales:	Liu, Benquan, Ji, Jiemei, Feng, Qing, Luo, Xi, Yan, Xiurong, Ni, Yuxia, He, Yajun, Mao, Zhongxuan, Liu, Jingchen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387603/ https://www.ncbi.nlm.nih.gov/pubmed/30858700 http://dx.doi.org/10.2147/DDDT.S192225

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