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Inhibition of Cerebral High-Mobility Group Box 1 Protein Attenuates Multiple Organ Damage and Improves T Cell-Mediated Immunity in Septic Rats

Sepsis remains one of the leading causes of mortality in intensive care units, but there is a shortage of effective treatments. A dysregulated host immune response and multiple organ injury are major factors for the pathogenesis and progression of sepsis, which require specific mechanism and treatme...

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Detalles Bibliográficos
Autores principales: Ren, Chao, Li, Xiu-hua, Wu, Yao, Dong, Ning, Tong, Ya-lin, Yao, Yong-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387733/
https://www.ncbi.nlm.nih.gov/pubmed/30881224
http://dx.doi.org/10.1155/2019/6197084