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Nonalcoholic Fatty Liver Disease in Diabetes. Part I: Epidemiology and Diagnosis
Nonalcoholic fatty liver disease (NAFLD) and diabetes are common metabolic disorders whose prevalence rates are expected to rise worldwide, corresponding to aging and increasingly obese populations. Compared to the general population (around 25%), 50% to 70% of people with diabetes have NAFLD, and N...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Diabetes Association
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387876/ https://www.ncbi.nlm.nih.gov/pubmed/30793550 http://dx.doi.org/10.4093/dmj.2019.0011 |
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author | Lee, Yong-ho Cho, Yongin Lee, Byung-Wan Park, Cheol-Young Lee, Dae Ho Cha, Bong-Soo Rhee, Eun-Jung |
author_facet | Lee, Yong-ho Cho, Yongin Lee, Byung-Wan Park, Cheol-Young Lee, Dae Ho Cha, Bong-Soo Rhee, Eun-Jung |
author_sort | Lee, Yong-ho |
collection | PubMed |
description | Nonalcoholic fatty liver disease (NAFLD) and diabetes are common metabolic disorders whose prevalence rates are expected to rise worldwide, corresponding to aging and increasingly obese populations. Compared to the general population (around 25%), 50% to 70% of people with diabetes have NAFLD, and NAFLD severity (including fibrosis) tends to be worsened by the presence of diabetes. NAFLD is considered an emerging risk factor for type 2 diabetes mellitus and a contributor to the development of chronic diabetes-related complications. This reciprocal relationship demonstrates the importance of confirming suspected NAFLD in patients with diabetes. Due to the invasive nature of liver biopsy to assess NAFLD status, various alternative non-invasive modalities have been developed and validated. Here, we summarized the epidemiology of NAFLD in patients with diabetes and reviewed currently available imaging modalities and biomarker-based prediction models for their ability to detect liver steatosis and/or fibrosis. |
format | Online Article Text |
id | pubmed-6387876 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Korean Diabetes Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-63878762019-03-04 Nonalcoholic Fatty Liver Disease in Diabetes. Part I: Epidemiology and Diagnosis Lee, Yong-ho Cho, Yongin Lee, Byung-Wan Park, Cheol-Young Lee, Dae Ho Cha, Bong-Soo Rhee, Eun-Jung Diabetes Metab J Review Nonalcoholic fatty liver disease (NAFLD) and diabetes are common metabolic disorders whose prevalence rates are expected to rise worldwide, corresponding to aging and increasingly obese populations. Compared to the general population (around 25%), 50% to 70% of people with diabetes have NAFLD, and NAFLD severity (including fibrosis) tends to be worsened by the presence of diabetes. NAFLD is considered an emerging risk factor for type 2 diabetes mellitus and a contributor to the development of chronic diabetes-related complications. This reciprocal relationship demonstrates the importance of confirming suspected NAFLD in patients with diabetes. Due to the invasive nature of liver biopsy to assess NAFLD status, various alternative non-invasive modalities have been developed and validated. Here, we summarized the epidemiology of NAFLD in patients with diabetes and reviewed currently available imaging modalities and biomarker-based prediction models for their ability to detect liver steatosis and/or fibrosis. Korean Diabetes Association 2019-02 2018-12-17 /pmc/articles/PMC6387876/ /pubmed/30793550 http://dx.doi.org/10.4093/dmj.2019.0011 Text en Copyright © 2019 Korean Diabetes Association http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Lee, Yong-ho Cho, Yongin Lee, Byung-Wan Park, Cheol-Young Lee, Dae Ho Cha, Bong-Soo Rhee, Eun-Jung Nonalcoholic Fatty Liver Disease in Diabetes. Part I: Epidemiology and Diagnosis |
title | Nonalcoholic Fatty Liver Disease in Diabetes. Part I: Epidemiology and Diagnosis |
title_full | Nonalcoholic Fatty Liver Disease in Diabetes. Part I: Epidemiology and Diagnosis |
title_fullStr | Nonalcoholic Fatty Liver Disease in Diabetes. Part I: Epidemiology and Diagnosis |
title_full_unstemmed | Nonalcoholic Fatty Liver Disease in Diabetes. Part I: Epidemiology and Diagnosis |
title_short | Nonalcoholic Fatty Liver Disease in Diabetes. Part I: Epidemiology and Diagnosis |
title_sort | nonalcoholic fatty liver disease in diabetes. part i: epidemiology and diagnosis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387876/ https://www.ncbi.nlm.nih.gov/pubmed/30793550 http://dx.doi.org/10.4093/dmj.2019.0011 |
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