Endodontic biofilms: contemporary and future treatment options

Apical periodontitis is a biofilm-mediated infection. The biofilm protects bacteria from host defenses and increase their resistance to intracanal disinfecting protocols. Understanding the virulence of these endodontic microbiota within biofilm is essential for the development of novel therapeutic p...

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Detalles Bibliográficos
Autores principales: Yoo, Yeon-Jee, Perinpanayagam, Hiran, Oh, Soram, Kim, A-Reum, Han, Seung-Hyun, Kum, Kee-Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Conservative Dentistry 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387897/
https://www.ncbi.nlm.nih.gov/pubmed/30834229
http://dx.doi.org/10.5395/rde.2019.44.e7
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author Yoo, Yeon-Jee
Perinpanayagam, Hiran
Oh, Soram
Kim, A-Reum
Han, Seung-Hyun
Kum, Kee-Yeon
author_facet Yoo, Yeon-Jee
Perinpanayagam, Hiran
Oh, Soram
Kim, A-Reum
Han, Seung-Hyun
Kum, Kee-Yeon
author_sort Yoo, Yeon-Jee
collection PubMed
description Apical periodontitis is a biofilm-mediated infection. The biofilm protects bacteria from host defenses and increase their resistance to intracanal disinfecting protocols. Understanding the virulence of these endodontic microbiota within biofilm is essential for the development of novel therapeutic procedures for intracanal disinfection. Both the disruption of biofilms and the killing of their bacteria are necessary to effectively treat apical periodontitis. Accordingly, a review of endodontic biofilm types, antimicrobial resistance mechanisms, and current and future therapeutic procedures for endodontic biofilm is provided.
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spelling pubmed-63878972019-03-04 Endodontic biofilms: contemporary and future treatment options Yoo, Yeon-Jee Perinpanayagam, Hiran Oh, Soram Kim, A-Reum Han, Seung-Hyun Kum, Kee-Yeon Restor Dent Endod Review Article Apical periodontitis is a biofilm-mediated infection. The biofilm protects bacteria from host defenses and increase their resistance to intracanal disinfecting protocols. Understanding the virulence of these endodontic microbiota within biofilm is essential for the development of novel therapeutic procedures for intracanal disinfection. Both the disruption of biofilms and the killing of their bacteria are necessary to effectively treat apical periodontitis. Accordingly, a review of endodontic biofilm types, antimicrobial resistance mechanisms, and current and future therapeutic procedures for endodontic biofilm is provided. The Korean Academy of Conservative Dentistry 2019-01-31 /pmc/articles/PMC6387897/ /pubmed/30834229 http://dx.doi.org/10.5395/rde.2019.44.e7 Text en Copyright © 2019. The Korean Academy of Conservative Dentistry https://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Yoo, Yeon-Jee
Perinpanayagam, Hiran
Oh, Soram
Kim, A-Reum
Han, Seung-Hyun
Kum, Kee-Yeon
Endodontic biofilms: contemporary and future treatment options
title Endodontic biofilms: contemporary and future treatment options
title_full Endodontic biofilms: contemporary and future treatment options
title_fullStr Endodontic biofilms: contemporary and future treatment options
title_full_unstemmed Endodontic biofilms: contemporary and future treatment options
title_short Endodontic biofilms: contemporary and future treatment options
title_sort endodontic biofilms: contemporary and future treatment options
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387897/
https://www.ncbi.nlm.nih.gov/pubmed/30834229
http://dx.doi.org/10.5395/rde.2019.44.e7
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