Cargando…

Editorial: Multi-Target-Directed Ligands (MTDL) as Challenging Research Tools in Drug Discovery: From Design to Pharmacological Evaluation

Detalles Bibliográficos
Autores principales:	Alcaro, Stefano, Bolognesi, Maria Laura, García-Sosa, Alfonso T., Rapposelli, Simona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387964/ https://www.ncbi.nlm.nih.gov/pubmed/30834243 http://dx.doi.org/10.3389/fchem.2019.00071

Ejemplares similares

SUN-717 SG-2 a Novel Multi-Target Directed Ligand (MTDL) for the Treatment of Neurodegenerative Diseases (NDDS)
por: Sestito, Simona, et al.
Publicado: (2020)

σ(2) Receptor and Its Role in Cancer with Focus on a MultiTarget Directed Ligand (MTDL) Approach
por: Abatematteo, Francesca Serena, et al.
Publicado: (2021)

Design and synthesis of new indole drug candidates to treat Alzheimer’s disease and targeting neuro-inflammation using a multi-target-directed ligand (MTDL) strategy
por: Lamie, Phoebe F., et al.
Publicado: (2022)

MTDL-EPDCLD: A Multi-Task Deep-Learning-Based System for Enhanced Precision Detection and Diagnosis of Corn Leaf Diseases
por: Dai, Dikang, et al.
Publicado: (2023)

Editorial: Protein–Protein Interactions: Drug Discovery for the Future
por: Rapposelli, Simona, et al.
Publicado: (2021)

Sustainable Drug Discovery of Multi-Target-Directed Ligands for Alzheimer’s Disease
por: Rossi, Michele, et al.
Publicado: (2021)

Editorial: Computational chemogenomics: In silico tools in pharmacological research and drug discovery
por: Sánchez-Cruz, Norberto, et al.
Publicado: (2023)

Editorial: Multi-target directed ligands for the treatment of cancer
por: Brindisi, Margherita, et al.
Publicado: (2022)

Riluzole–Rasagiline Hybrids: Toward the Development of Multi-Target-Directed Ligands for Amyotrophic Lateral Sclerosis
por: Albertini, Claudia, et al.
Publicado: (2022)

Editorial: New insights into the mechanisms of resistance to anti-cancer drugs
por: Bertoni, Francesco, et al.
Publicado: (2022)

The Mu.Ta.Lig. Chemotheca: A Community-Populated Molecular Database for Multi-Target Ligands Identification and Compound-Repurposing
por: Ortuso, Francesco, et al.
Publicado: (2018)

Editorial: The Challenge Posed by New Synthetic Opioids: Pharmacology and Toxicology
por: Pichini, Simona, et al.
Publicado: (2019)

Editorial: New approaches for the discovery of GPCR ligands
por: Morales, Paula, et al.
Publicado: (2023)

Editorial of Special Column on Antiviral Drug Discovery and Pharmacology
por: Wang, Jun, et al.
Publicado: (2022)

Editorial: Insights in Experimental Pharmacology and Drug Discovery: 2021
por: Trostchansky, Andres, et al.
Publicado: (2022)

Editorial: Women in experimental pharmacology and drug discovery: 2021
por: Rižner, Tea Lanišnik, et al.
Publicado: (2022)

Editorial: Insights in experimental pharmacology and drug discovery: 2022
por: Latini, Alexandra, et al.
Publicado: (2023)

Editorial: Debates in cardiovascular pharmacology and drug discovery: 2022
por: Xu, Keman, et al.
Publicado: (2023)

The Use of Zidovudine Pharmacophore in Multi-Target-Directed Ligands for AIDS Therapy
por: Bianco, Maria da Conceição Avelino Dias, et al.
Publicado: (2022)

Editorial: Methods and application in experimental pharmacology and drug discovery: 2021
por: Polito, Letizia, et al.
Publicado: (2022)

Editorial: Model organisms in experimental pharmacology and drug discovery 2022
por: Nainu, Firzan, et al.
Publicado: (2023)

Editorial: Spotlight on artificial intelligence in experimental pharmacology and drug discovery
por: Schöning, Verena, et al.
Publicado: (2023)

From tryptamine to the discovery of efficient multi-target directed ligands against cholinesterase-associated neurodegenerative disorders
por: Wu, Junbo, et al.
Publicado: (2022)

Discovery of Novel Tryptanthrin Derivatives with Benzenesulfonamide Substituents as Multi-Target-Directed Ligands for the Treatment of Alzheimer’s Disease
por: Wang, Guoxing, et al.
Publicado: (2023)

Hydrogen Sulfide: A Worthwhile Tool in the Design of New Multitarget Drugs
por: Sestito, Simona, et al.
Publicado: (2017)

Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity
por: Dichiara, Maria, et al.
Publicado: (2023)

Cannabinoid ligands, receptors and enzymes: Pharmacological tools and therapeutic potential
por: Hourani, Wafa, et al.
Publicado: (2018)

Editorial: Brief research reports in experimental pharmacology and drug discovery: 2022
por: Hassan, Tahsin, et al.
Publicado: (2023)

Editorial: Peptidomimetics: Synthetic Tools for Drug Discovery and Development
por: Del Gatto, Annarita, et al.
Publicado: (2021)

Editorial: Computational and Experimental Approaches in Multi-target Pharmacology
por: Anastasio, Thomas J.
Publicado: (2017)

Ligand Screening Systems for Human Glucose Transporters as Tools in Drug Discovery
por: Schmidl, Sina, et al.
Publicado: (2018)

Pharmacological Actions of Multi-Target-Directed Evodiamine
por: Yu, Hui, et al.
Publicado: (2013)

Editorial: Metabolomics as a tool in ethnobotany-driven drug discoveries
por: Makunga, Nokwanda, et al.
Publicado: (2022)

High‐Throughput Kinetic Analysis for Target‐Directed Covalent Ligand Discovery
por: Craven, Gregory B., et al.
Publicado: (2018)

Editorial: Drug-drug interactions in pharmacology
por: Pichini, Simona, et al.
Publicado: (2023)

Editorial: Pharmacological Aspects of Ligand-Gated Ion Channels as Targets of Natural and Synthetic Agents
por: Mattei, César, et al.
Publicado: (2022)

Editorial: Identification of novel biomarkers for pancreatic and hepatocellular cancers
por: Matteucci, Laura, et al.
Publicado: (2022)

Discovery of a Novel Chemical Class of mGlu(5) Allosteric Ligands with Distinct Modes of Pharmacology
por: Hammond, Alexis S., et al.
Publicado: (2010)

Editorial for Special Issue—“Early-Stage Drug Discovery: Advances and Challenges”
por: Sippl, Wolfgang
Publicado: (2023)

Editorial: MSPP 34th scientific meeting: Pharmacological perspectives on natural products in drug discovery
por: Shaikh, Mohd. Farooq, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_o37vu7ag1jk7vb94u9a0r7tj45