An in vitro ADME and in vivo Pharmacokinetic Study of Novel TB-Active Decoquinate Derivatives

Tuberculosis (TB) is currently the leading cause of mortality due to an infectious disease, despite the existence of multiple effective first-line and second-line drugs. The current anti-TB regimen requires a prolonged treatment period of around 6 months and is only efficacious against drug-sensitiv...

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Detalles Bibliográficos
Autores principales: Tanner, Lloyd, Haynes, Richard K., Wiesner, Lubbe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387968/
https://www.ncbi.nlm.nih.gov/pubmed/30833898
http://dx.doi.org/10.3389/fphar.2019.00120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387968/
https://www.ncbi.nlm.nih.gov/pubmed/30833898
http://dx.doi.org/10.3389/fphar.2019.00120

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