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An in vitro ADME and in vivo Pharmacokinetic Study of Novel TB-Active Decoquinate Derivatives
Tuberculosis (TB) is currently the leading cause of mortality due to an infectious disease, despite the existence of multiple effective first-line and second-line drugs. The current anti-TB regimen requires a prolonged treatment period of around 6 months and is only efficacious against drug-sensitiv...
Autores principales: | Tanner, Lloyd, Haynes, Richard K., Wiesner, Lubbe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387968/ https://www.ncbi.nlm.nih.gov/pubmed/30833898 http://dx.doi.org/10.3389/fphar.2019.00120 |
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