Cardiovascular Insufficiency, Abdominal Sepsis, and Patients' Age Are Associated with Decreased Paraoxonase-1 (PON1) Activity in Critically Ill Patients with Multiple Organ Dysfunction Syndrome (MODS)

Oxidative stress and uncontrolled inflammation are hallmarks of sepsis, leading to organ failure and death. As demonstrated in animal studies, oxidative stress can be alleviated by antioxidant therapies. Paraoxonase-1 (PON1) is a serum-based antioxidant, anti-inflammatory agent, detoxifier, and quor...

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Detalles Bibliográficos
Autores principales: Bednarz-Misa, Iwona, Mierzchala-Pasierb, Magdalena, Lesnik, Patrycja, Placzkowska, Sylwia, Kedzior, Krzysztof, Gamian, Andrzej, Krzystek-Korpacka, Malgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388350/
https://www.ncbi.nlm.nih.gov/pubmed/30886652
http://dx.doi.org/10.1155/2019/1314623

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